Thursday, May 17, 2007
This is just a snapshot of Day One. For full details, please download our brochure.
| 8:00 | Registration & Morning Coffee |
| 8:30 | Conference Chair's Opening Remarks
Rich Miller, DVM, PhD, DACVP
VP, Safety Assessment
GLAXOSMITHKLINE
|
| 8:45 | Advancements & Updates in Prediction Techniques |
James W. Freston, MD, PhD
Professor of Medicine Emeritus & Boehringer Ingelheim Chair of Clinical Pathology
UNIVERSITY OF CONNECTICUT HEALTH CENTER
|
9:30 | PANEL DISCUSSION
The Future - Integration and the Prediction Direction |
Michael D. DuVall, DVM, PhD
Group Leader Toxicology & Safety Pharm., Global Preclinical Safety
ABBOTT LABORATORIES
William B Mattes, PhD
Director of Toxicology
THE CRITICAL PATH INSTITUTE
Jeff Lawrence
Director of Biochemical Toxicology & Biomarkers
AMGEN
Donna Mendrick, PhD
Scientific Fellow & VP Toxicogenomics
GENE LOGIC
Christine Hunt, MD
Director of Global Hepatic Safety, Clinical Safety
GLAXOSMITHKLINE
James W. Freston, MD, PhD
Professor of Medicine Emeritus & Boehringer Ingelheim Chair of Clinical Pathology
UNIVERSITY OF CONNECTICUT HEALTH CENTER
|
| 10:15 | 30-Minute Break |
| 10:45 | Monitor Liver Function in Pre-Clinical to Identify Potential Liver Toxicity in Humans |
Michael D. DuVall, DVM, PhD
Group Leader Toxicology & Safety Pharm., Global Preclinical Safety
ABBOTT LABORATORIES
|
| 11:30 | Strategies to Reduce NCE Attrition Due to Liver Toxicity-Designing Novel Screening Methods |
Yvonne Will, PhD
Group Leader: Molecular, Cellular & Biochemical Toxicology
PFIZER
|
| 12:15 | Luncheon |
| 1:30 | Use of Pharmacogenomics to Discover Translational Biomarkers |
Donna Mendrick, PhD
Scientific Fellow and VP Toxicogenomics
GENE LOGIC, INC.
|
| 2:15 | Is it the Liver or Something Else? Overcome Challenges Associated with Testing for Hepatotoxicity |
Debra Laskin, PhD
Professor & Chair, Dept. of Pharmacology & Toxicology
RUTGERS UNIVERSITY
|
| 3:00 | Determinants of Susceptibility to Drug-Induced Liver Injury — Inflammatory Stress and Animal Models |
Robert Roth, PhD
Assoc. Director for Toxicology Research, National Center for Food Safety & Toxicology
MICHIGAN STATE UNIVERSITY
|
| 3:45 | 15-Minute Break |
| 4:00 | The Clinical Presentation & Evaluation of Drug-Induced Liver Injury: Is this Disease or Adaptation? |
Christine Hunt, MD
Director of Global Hepatic Safety, Clinical Safety
GLAXOSMITHKLINE
|
| 4:45 | Day One Concludes |
