In 2010, we are combining the Cell Based Assays and Bioanalytical Development Conferences to provide one comprehensive event that encompasses both areas, yet leaving time to dive deeply into the content of each one using separate track sessions.

We are currently researching the topics for October 4-6 in San Francisco, if you have an interesting story to tell, please contact program director, Anne Reel 919-676-0306 or AReel@iirusa.com.

Topics we are looking into include:

• Fc gamma binding ADCC, FC effecter binding and function, Assessment of FC functionality and F binding ADCC
• alternative assays to using ADCC to measure FC/FCR binding
• ADC matrix interference
• QA Assays development &  QC assay qualification
• Antiviral reporter assays
• Cell based functional assays
• Technical Platform qualification and evaluate long term usefulness of new  technologies
• How to rapidly develop assays for new indication where there is no established systems
• Determine limit of detection of assay and complexity of MoA
• Case studies on cell based potency assays, methodology selection cellular mechanisms
• Strategies for characterizing new therapeutics for efficacy
• Improvements in innovation and automation
• Surrogate for NK cells –example NK cell line
• Antibody drug conjugate case studies
• Total and bound assays-free vs total  drug assays examples
• Technologies to measure drug target interactions

Why should you attend?

• To learn from other in industry how they overcome issues
• To update recent  research analysis and methods development
• To gain insight into the state of the art bioanalytical methods
• To learn where BA field in respect to measuring total vs free drug target in pre clinical and clinical studies

Featured Presentations

Use Flow Cytometry for Potency Assays and Cell Based Assays
Harald Kropshofer, Pharmaceutical Research, F. Hoffmann-La Roche

A Neuronal Cell-based Assay for Highly Sensitive Detection of Pharmaceutical Preparations of BoNT/A and Patient Neutralizing Serum Antibodies
Eric A. Johnson, Professor, Department of Bacteriology, Food Research Institute, University of Wisconsin, Madison

Resources